Care + Calamine Lotion BP is a mild astringent and antiseptic. Calamine Lotion is very safe to use and has a soothing, cooling effect on the skin. Care+ Calamine Lotion Bp contains calamine and zinc oxide that creates symptomatic relief from mild sunburn and other minor skin conditions such as chicken pox. It can also be used for itchy, irritated and sore skin, thanks to its cooling and soothing effect on the skin.